India, Oct. 24 -- Experts at BJ Medical College (BJMC) and Sassoon General Hospital (SGH) will, for the first time, conduct targeted next-generation sequencing (tNGS) to identify drug-resistance mutations in tuberculosis (TB) patients.

According to officials, the initiative aims to improve diagnosis and help doctors select more effective treatments for drug-resistant TB (DR-TB).

NGS targets specific regions of the genome. It focuses on sequencing a select set of genes or gene regions that have known or suspected associations with a specific pathogen, lineage, or phenotype. The tNGS approach offers rapid and detailed genetic information across multiple gene regions. It addresses key challenges associated with conventional phenotypic drug...