ALEXANDRIA, Va., July 16 -- United States Patent no. 12,668,780, issued on June 30, was assigned to ZHEJIANG UNIVERSITY (Hangzhou, China).
"Macrophage-specific chimeric antigen receptor, controllable polarized monocyte/macrophage expressing the receptor, and preparation method and use thereof" was invented by Jin Zhang (Hangzhou, China), Anhua Lei (Hangzhou, China) and Lin Tian (Hangzhou, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are a macrophage-specific chimeric antigen receptor, a controllable polarized monocyte/macrophage expressing the receptor, and a preparation method and application thereof, relating to the field of biotechnology. The present disclosure provides a chimeric antigen...