ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,699,075, issued on Aug. 4, was assigned to ZHAOKE (GUANGZHOU) OPHTHALMOLOGY PHARMACEUTICAL Ltd. (Guangzhou, China).

"Method for the analysis of related substances in cyclosporine a preparation, and use thereof" was invented by Zhijun Xie (Guangzhou, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for analysis of related substances in a cyclosporine A preparation is provided. Chromatographic conditions for the method are as follows: a detection wavelength: 210 nm to 230 nm; a column temperature: 50deg deg C. to 60deg C.; a flow rate: 0.8 mL/min to 1.5 mL/min; a mobile phase A: acetonitrile (0.085% phosphoric acid); a mobile phase B: isopropa...