US Patent Issued to YALE UNIVERSITY on July 21 for "Interleukin-18 variants and methods of use" (Connecticut Inventors)

ALEXANDRIA, Va., July 21 -- United States Patent no. 12,685,759, issued on July 21, was assigned to YALE UNIVERSITY.

"Interleukin-18 variants and methods of use" was invented by Aaron Ring (New Haven, Conn.), Ting Zhou (New Haven, Conn.) and Suzanne Fischer (New Haven, Conn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides compositions and methods comprising an activator of interleukin-18 (IL-18) activity for use in therapeutic and non-therapeutic applications. The activator provides IL-18 signaling activity even in the presence of an inhibitory molecule 5 such as IL-18 binding protein (IL-18BP)."

The patent was filed on Jan. 20, 2023, under Application No. 18/157,385.

*For fur...