US Patent Issued to Xyzagen on Oct. 27 for "Prodrugs of Kv7 channel openers" (North Carolina Inventors)

ALEXANDRIA, Va., Oct. 27 -- United States Patent no. 12,774,267, issued on Oct. 27, was assigned to Xyzagen Inc. (Pittsboro, N.C.).

"Prodrugs of Kv7 channel openers" was invented by Christopher S. Crean (Pittsboro, N.C.) and Edward G. Brown (Cary, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Prodrugs of pharmacologically active 1,2,4-triaminobenzene derivatives of the General Formula (I); or pharmaceutically acceptable salts thereof, where the symbols R1, R2, R3, R4, R5 and R6a, R6b, and R6c and where the symbol Z are defined. Methods for the synthesis, purification, testing and use as prodrugs of pharmacologically-active agents at Kv7 ion channels are provided."

The patent was filed on March 20, 202...