US Patent Issued to XLIFESC on May 12 for "T cell receptor recognising KRAS mutation and encoding sequence thereof" (Chinese Inventors)

ALEXANDRIA, Va., May 12 -- United States Patent no. 12,624,084, issued on May 12, was assigned to XLIFESC LTD. (Guangdong, China).

"T cell receptor recognising KRAS mutation and encoding sequence thereof" was invented by Jing Hu (Guangdong, China) and Hanli Sun (Guangdong, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided is a T cell receptor (TCR) capable of specifically binding to KRAS G12V mutant antigens; the mutant antigen short peptide VVGAVGVGK is capable of forming a complex with HLA A1101, and the TCR specifically binds to said complex. Also provided in the present invention are a nucleic acid molecule encoding the TCR and a vector comprising the nucleic acid molecule. Also provided are ...