US Patent Issued to X-Chem on April 21 for "Methods of creating and screening DNA-encoded libraries" (Massachusetts Inventor)

ALEXANDRIA, Va., April 21 -- United States Patent no. 12,606,817, issued on April 21, was assigned to X-Chem Inc. (Waltham, Mass.).

"Methods of creating and screening DNA-encoded libraries" was invented by Richard W. Wagner (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention features a number of methods for identifying one or more compounds that bind to a biological target. The methods include synthesizing a library of compounds, wherein the compounds contain a functional moiety having one or more diversity positions. The functional moiety of the compounds is operatively linked to an initiator oligonucleotide that identifies the structure of the functional moiety."

The pat...