US Patent Issued to Wisconsin Alumni Research Foundation on June 9 for "Human pluripotent stem cell-based models for predictive developmental neural toxicity" (Wisconsin Inventors)

ALEXANDRIA, Va., June 9 -- United States Patent no. 12,649,906, issued on June 9, was assigned to Wisconsin Alumni Research Foundation (Madison, Wis.).

"Human pluripotent stem cell-based models for predictive developmental neural toxicity" was invented by James A. Thomson (Madison, Wis.), William L. Murphy (Waunakee, Wis.), Charles D. Page (Sun Prairie, Wis.), Michael P. Schwartz (Madison, Wis.) and Zhonggang Hou (Madison, Wis.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to three-dimensional (3D) tissue constructs and methods of using such 3D tissue constructs to screen for neurotoxic agents. In particular, provided herein are methods of producing and using complex, highly un...