ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,250, issued on March 17, was assigned to WIGEN BIOMEDICINE TECHNOLOGY (SHANGHAI) Co. LTD. (Shanghai).

"1,2,4-triazolone derivative as DHODH inhibitor, and preparation method therefor and use thereof" was invented by Yuli Xie (Shanghai), Houxing Fan (Shanghai) and Lihui Qian (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a 1,2,4-triazolone derivative as a DHODH inhibitor, a preparation method therefor and use thereof. Specifically, the present invention relates to a compound of general formula (1), a preparation method therefor, and use of the compound of general formula (1) and an isomer, a crystalline for...