ALEXANDRIA, Va., Feb. 24 -- United States Patent no. 12,559,505, issued on Feb. 24, was assigned to WIGEN BIOMEDICINE TECHNOLOGY (SHANGHAI) Co. LTD. (Shanghai).

"IDH mutant inhibitor and use thereof" was invented by Yuli Xie (Shanghai), Houxing Fan (Shanghai) and Lihui Qian (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a compound of general formula (1a) or general formula (1b) and a method for preparing the same, and use of the compound of general formula (1a) or general formula (1b) and an isomer, a crystalline form, a pharmaceutically acceptable salt, a hydrate or a solvate thereof as an irreversible inhibitor for an IDH mutant in preparing a medicament for resis...