US Patent Issued to Wenzhou Institute, University of Chinese Academy of Sciences on March 3 for "Cyclic Gd (III) complex and preparation method and use thereof" (Chinese Inventors)

ALEXANDRIA, Va., March 3 -- United States Patent no. 12,565,503, issued on March 3, was assigned to Wenzhou Institute, University of Chinese Academy of Sciences (Zhejiang, China).

"Cyclic Gd (III) complex and preparation method and use thereof" was invented by Lixiong Dai (Zhejiang, China), Weiyuan Xu (Zhejiang, China) and Fangfu Ye (Zhejiang, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides a cyclic Gd (III) complex with a chemical structure shown in formula I, where a ring structure of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) is used as a parent ring, lipophilic groups R' and R" in formula I are respectively introduced to a Alpha-position of phenyl...