ALEXANDRIA, Va., May 12 -- United States Patent no. 12,625,133, issued on May 12, was assigned to Waters Technologies Corp. (Milford, Mass.).

"Chemical denaturation for oligonucleotide analysis" was invented by Matthew A Lauber (North Smithfield, R.I.), Jennifer M. Nguyen (Uxbridge, Mass.), Xiaoxiao Liu (Natick, Mass.) and Michael Donegan (Charlton, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides compositions and methods for sample processing, particularly for oligonucleotide analysis e.g. analysis of formulated nucleic acid drugs. A composition for pretreating at least one target nucleic acid in a biological mixture provided herein includes a chaotropic agent selected fr...