US Patent Issued to Vrije Universiteit Brussel on Nov. 3 for "Combination of nucleic acid regulatory elements and methods and uses thereof" (Belgian Inventors)

ALEXANDRIA, Va., Nov. 3 -- United States Patent no. 12,779,052, issued on Nov. 3, was assigned to Vrije Universiteit Brussel (Brussels).

"Combination of nucleic acid regulatory elements and methods and uses thereof" was invented by Thierry Vandendriessche (Brussels) and Lay Khim Chuah (Bierbeek, Belgium).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are nucleic acid sequences that function as skeletal muscle- and diaphragm muscle-specific cis-regulatory elements (CREs). The disclosed CREs are operably linked to heterologous promoters to enhance muscle-specific expression of genes. Also provided are expression cassettes and vectors comprising the disclosed cis-regulatory elements in combinati...