ALEXANDRIA, Va., Nov. 3 -- United States Patent no. 12,782,250, issued on Nov. 3, was assigned to Vrije Universiteit Brussel (Brussels) and VIB VZW (Ghent, Belgium).

"Means and methods for time-resolved sampling" was invented by Rouslan Efremov (Ghent, Belgium), Stefania Torino (Brussels) and Raf Claessens (Neerijse, Belgium).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to the field of time-resolved protein sampling, more specifically for use in structural biology, even more specifically for structural analysis of proteins by Cryogenic-electron microscopy (Cryo-EM). The invention provides for methods and devices for preparing vitrified samples for transmission electron microsco...