US Patent Issued to Vanderbilt University on July 21 for "Amyloid-binding compounds and methods of use thereof" (Tennessee Inventors)

ALEXANDRIA, Va., July 21 -- United States Patent no. 12,687,540, issued on July 21, was assigned to Vanderbilt University (Nashville, Tenn.).

"Amyloid-binding compounds and methods of use thereof" was invented by Wellington Pham (Nashville, Tenn.), Richard A. McClure (Nashville, Tenn.) and William James Behof (Nashville, Tenn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method of screening for amyloid-binding compounds, amyloid-binding compounds, and a method of detecting amyloid-Beta (Abeta) plaques in a subject are disclosed. The method of screening for amyloid-binding compounds includes combining amyloid, a dye, and at least one test compound to form a sample solution; equilibrating the sample soluti...