ALEXANDRIA, Va., Sept. 8 -- United States Patent no. 12,729,236, issued on Sept. 8, was assigned to VALITOR INC. (Berkeley, Calif.).
"Hydrophilic linkers for antibody or DARPin conjugates" was invented by Wesley M. Jackson (Berkley, Calif.), Amy A. Twite (Berkeley, Calif.) and Livia Wilz Brier (Berkeley, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure is directed to peptide-polymer conjugates utilizing hydrophilic linkers, and their use in treating diseases or disorders. In one embodiment, the present invention provides a conjugate of Formula I: (X-Y)n-Z Formula (I) wherein each X is independently a peptide having a molecular weight of from about 5 kDa to about 200 kDa; each Y is...