US Patent Issued to UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION on May 26 for "HLA class II deficient cells, HLA class I deficient cells capable of expressing HLA class II proteins, and uses thereof" (Washington Inventors)

ALEXANDRIA, Va., May 26 -- United States Patent no. 12,636,354, issued on May 26, was assigned to UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle).

"HLA class II deficient cells, HLA class I deficient cells capable of expressing HLA class II proteins, and uses thereof" was invented by David W. Russell (Seattle) and Roli K. Hirata (Seattle).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides isolated primate cells preferably human cells that comprise a genetically engineered disruption in a human leukocyte antigen (HLA) class II-related gene, which results in deficiency in MHC class II expression and function. This invention also provides isolated cells further comp...