ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,770,229, issued on Oct. 20, was assigned to University of Southern California (Los Angeles).

"Hyperspectral imaging system with hybrid unmixing" was invented by Hsiao-Ju Chiang (Los Angeles), Eun Sang Koo (Los Angeles), Scott E. Fraser (Los Angeles) and Francesco Cutrale (Los Angeles).

According to the abstract* released by the U.S. Patent & Trademark Office: "Hybrid unmixing technique (HyU) of this disclosure may provide enhanced imaging of multiplexed fluorescence labels, enabling longitudinal imaging of multiple fluorescent signals with reduced illumination intensities. This disclosure generally relates to imaging systems. This disclosure relates to hyperspectral imaging systems. ...