US Patent Issued to UNIVERSITY OF SOUTH CAROLINA on June 2 for "Inhibitors of lysyl oxidases" (South Carolina Inventors)

ALEXANDRIA, Va., June 2 -- United States Patent no. 12,642,791, issued on June 2, was assigned to UNIVERSITY OF SOUTH CAROLINA (Columbia, S.C.).

"Inhibitors of lysyl oxidases" was invented by Ozgur Sahin (Lexington, S.C.), Campbell McInnes (Irmo, S.C.), Ozge Saatci (Columbia, S.C.), Chad Beneker (Irmo, S.C.), Abdol-Hossein Rezaeian (Lexington, S.C.) and Metin Cetin (Columbia, S.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are compounds that block the activity of LOX family members having good IC50 values, no cellular toxicity below 10 MuM, induce sensitization of the cells to doxorubicin, strong activity in a recombinant LOX/LOXL2 activity, and a chemical structure that is drug-like and...