ALEXANDRIA, Va., Sept. 8 -- United States Patent no. 12,729,224, issued on Sept. 8, was assigned to University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh).

"Targeting MYD88 gene in vitro and in vivo" was invented by Samira Kiani (Los Altos, Calif.) and Tahere Mokhtari (Pittsburgh).

According to the abstract* released by the U.S. Patent & Trademark Office: "A non-naturally occurring zinc finger protein, wherein the zinc finger protein specifically binds to the promoter region of the Myd88 gene, is provided, as well as related polynucleotides, vectors, cells, and pharmaceutical compositions. In some aspects, the zinc finger protein comprises one or more repressors. Pharmaceutical compositions comprising a pharm...