US Patent Issued to UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION on Aug. 25 for "T cell receptors targeting defective DNA repair proteins" (Pennsylvania Inventors)

ALEXANDRIA, Va., Aug. 25 -- United States Patent no. 12,715,902, issued on Aug. 25, was assigned to UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh).

"T cell receptors targeting defective DNA repair proteins" was invented by Udai Shankar Kammula (Pittsburgh), Ghanshyam Singh Yadav (Pittsburgh) and Chetana Bhaskarla (Pittsburgh).

According to the abstract* released by the U.S. Patent & Trademark Office: "This document provides isolated immune cells that include an exogenous T cell receptor (TCR) having affinity for an Ataxia-Telangiesctasia Mutated (ATM) peptide, an exogenous TCR having affinity for an AT-rich interactive domain-containing protein 1A (ARID1A) peptide, or both an exogenous TCR having affi...