ALEXANDRIA, Va., July 15 -- United States Patent no. 12,661,412, issued on June 23, was assigned to University of Massachusetts (Westborough, Mass.).

"Method to enhance the efficiency of systemic AAV gene delivery to the central nervous system" was invented by Miguel Sena Esteves (Worcester, Mass.), Ana Rita Batista (Worcester, Mass.) and Sourav Roy Choudhury (Worcester, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure relates, in some aspects, to compositions and methods for enhanced delivery of a transgene to the central nervous system (CNS) of a subject. In some embodiments, the transgene is delivered by recombinant AAV (rAAV). In some embodiments, the method of enhancing transgene deli...