US Patent Issued to UNIVERSITY OF MASSACHUSETTS on July 28 for "Modified oligonucleotides targeting SNPs" (Massachusetts Inventors)

ALEXANDRIA, Va., July 28 -- United States Patent no. 12,692,498, issued on July 28, was assigned to UNIVERSITY OF MASSACHUSETTS (Westborough, Mass.).

"Modified oligonucleotides targeting SNPs" was invented by Anastasia Khvorova (Westborough, Mass.), Julia Alterman (Worcester, Mass.), Faith Conroy (Worcester, Mass.), Edith Pfister (Boxborough, Mass.), Neil Aronin (Newtonville, Mass.) and Ken Yamada (Boston).

According to the abstract* released by the U.S. Patent & Trademark Office: "Novel oligonucleotides that enhance silencing of the expression of a gene containing a single nucleotide polymorphism (SNP) relative to the expression of the corresponding wild-type gene are provided. Methods of using novel oligonucleotides that enhance silenci...