US Patent Issued to University of Massachusetts on April 21 for "Compositions and methods for modulating RPGR expression" (Massachusetts Inventors)

ALEXANDRIA, Va., April 21 -- United States Patent no. 12,606,825, issued on April 21, was assigned to University of Massachusetts (Westborough, Mass.).

"Compositions and methods for modulating RPGR expression" was invented by Hemant Khanna (Worcester, Mass.) and Laura Moreno Leon (Worcester, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Aspects of the disclosure relate to compositions and methods for modulating expression of certain RPGR retinitis pigmentosa GTPase regulator (RPGR) proteins in a cell or subject. In some embodiments the disclosure provides expression vectors encoding one or more RPGR proteins and/or one or more inhibitory nucleic acids that target certain isoforms of RPGR, for example ...