US Patent Issued to UNIVERSITY OF HOUSTON SYSTEM, Trustees of Tufts College on May 12 for "Pyrido[2,3-dpyrimidin-7-ones and related compounds as inhibitors of protein kinases" (Texas, Massachusetts Inventors)

ALEXANDRIA, Va., May 12 -- United States Patent no. 12,624,032, issued on May 12, was assigned to UNIVERSITY OF HOUSTON SYSTEM (Houston) and Trustees of Tufts College (Medford, Mass.).

"Pyrido[2,3-dpyrimidin-7-ones and related compounds as inhibitors of protein kinases" was invented by Gregory Cuny (Houston), Sameer Nikhar (Houston) and Alexei Degterev (Brookline, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Identified compounds demonstrate protein kinase inhibitory activity. More specifically, the compounds are demonstrated to inhibit receptor interacting kinase 2 (RIPK2) and/or Activin-like kinase 2 (ALK2). Compounds that are either dual RIPK2/ALK2 inhibitors or that preferentially inhibit RIPK2 or...