ALEXANDRIA, Va., March 3 -- United States Patent no. 12,565,513, issued on March 3, was assigned to University of Florida Research Foundation Inc. (Gainesville, Fla.).

"Synthesis of glycosphingolipids" was invented by Zhongwu Guo (Gainesville, Fla.) and Qingjiang Li (Gainesville, Fla.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are methods of synthesizing glycolipids. The methods combine chemical and enzymatic transformations to rapidly provide diverse natural and functionalized glycolipids in a high convergent matter. Stepwise enzymatic elongation of a carbohydrate chain of a common glycolipid precursor, compound (1), provides glycan intermediates of Formula (II), using sugar-nucleotides as glyc...