ALEXANDRIA, Va., April 21 -- United States Patent no. 12,605,466, issued on April 21, was assigned to University of Florida Research Foundation Inc. (Gainesville, Fla.).
"Enhanced human opsin promoter for rod specific expression" was invented by Frank M. Dyka (Gainesville, Fla.) and William W. Hauswirth (Gainesville, Fla.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides short enhanced human opsin promoters for rod-specific expression that satisfy a need in the art for promoters that are able to control transgene expression both efficiently and selectively in rod cells, with little to no off-target expression in other photoreceptor cells. The disclosure provides vector constructs...