ALEXANDRIA, Va., March 3 -- United States Patent no. 12,565,474, issued on March 3, was assigned to University of Florida Research Foundation Inc. (Gainesville, Fla.) and Smithsonian Institution (Washington).

"Discovery, total synthesis, and bioactivity of doscadenamides" was invented by Hendrik Luesch (Gainesville, Fla.), Xiao Liang (Gainesville, Fla.), Susan Matthew (Houston), Jason C. Kwan (Gainesville, Fla.), Qi-Yin Chen (Gainesville, Fla.) and Valerie J. Paul (Fort Pierce, Fla.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention is directed towards compounds (e.g., Formulae (I)-(IX)), their mechanism of action, processes to prepare the compounds, methods of activating quorum sensing signaling a...