ALEXANDRIA, Va., March 24 -- United States Patent no. 12,583,916, issued on March 24, was assigned to University of Connecticut (Farmington, Conn.) and JOSLIN DIABETES CENTER INC. (Boston).

"Methods to improve glucose tolerance in a subject by administering an antibody that binds to extracellular human metallothionein 1A (MT1A)" was invented by Michael A. Lynes (Farmington, Conn.), Yu-Hua Tseng (Boston) and Matthew D. Lynes (Boston).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are methods for use of an antibody, such as a monoclonal antibody and/or a humanized antibody, that binds to extracellular human metallothionein 1A (MT1A), or an antigenic binding fragment thereof, to improve glucose toleranc...