US Patent Issued to University of Cincinnati on April 21 for "Engineered probiotics for treatment and immunity against viruses" (Ohio Inventors)

ALEXANDRIA, Va., April 21 -- United States Patent no. 12,605,413, issued on April 21, was assigned to University of Cincinnati (Cincinnati).

"Engineered probiotics for treatment and immunity against viruses" was invented by Nalinikanth Kotagiri (West Chester, Ohio) and Nitin S. Kamble (Cincinnati).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention involves an engineered probiotic bacterium comprising a heterologous nucleic acid, where the heterologous nucleic acid comprises a nucleic acid sequence encoding an anti-spike glycoprotein nanobody of a coronavirus. In one embodiment, the bacterium is Escherichia coli Nissle 1917. In another embodiment, the anti-spike glycoprotein nanobody appears ...