US Patent Issued to University Health Network on March 31 for "Cancer detection and classification using methylome analysis" (Canadian Inventors)

ALEXANDRIA, Va., March 31 -- United States Patent no. 12,592,321, issued on March 31, was assigned to University Health Network (Toronto).

"Cancer detection and classification using methylome analysis" was invented by Scott Victor Bratman (Toronto), Justin Matthew Burgener (Toronto) and Daniel Diniz De Carvalho (Toronto).

According to the abstract* released by the U.S. Patent & Trademark Office: "This is described herein, a method of capturing cell-free methylated DNA from a sample having less than 100 mg of cell-free DNA, comprising the steps of: subjecting the sample to library preparation to permit subsequent sequencing of the cell-free methylated DNA; adding a first amount of filler DNA to the sample, wherein at least a portion of the...