US Patent Issued to University Health Network on March 17 for "T cell receptors and methods of use thereof" (Canadian Inventors)

ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,287, issued on March 17, was assigned to University Health Network (Toronto).

"T cell receptors and methods of use thereof" was invented by Naoto Hirano (Toronto), Kenji Murata (Toronto) and Kayoko Saso (Toronto).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure is directed recombinant T cell receptors capable of binding a tyrosinase epitope, a MAGA-A1 epitope, a MART1 epitope, a MAGE-A3 epitope, or an SSX2 epitope and nucleic acid molecules encoding the same. In some embodiments, the nucleic acid molecules further comprise a second nucleotide sequence, wherein the second nucleotide sequence or the polypeptide encoded by the seco...