US Patent Issued to UNIVERSITY HEALTH NETWORK on June 30 for "Method for expansion of double negative regulatory T cells" (Canadian Inventors)

ALEXANDRIA, Va., July 16 -- United States Patent no. 12,668,778, issued on June 30, was assigned to UNIVERSITY HEALTH NETWORK (Toronto).

"Method for expansion of double negative regulatory T cells" was invented by Li Zhang (Toronto), Paulina Achita (Mississauga, Canada), Jongbok Lee (Toronto), Dalam Ly (Toronto) and Dzana Dervovic (Toronto).

According to the abstract* released by the U.S. Patent & Trademark Office: "There is provided herein a method for expanding human CD4-CD8- regulatory T cells (DN Tregs) from a population of cells comprising DN Tregs, comprising: culturing the population of cells with artificial antigen presenting cells (APCs), preferably the DN Tregs are AlphaBeta-TCR+CD56- or alternatively GammaDelta-TCR+."

The pate...