ALEXANDRIA, Va., June 2 -- United States Patent no. 12,642,868, issued on June 2, was assigned to UNIVERSITEIT GENT (Ghent, Belgium).
"Therapeutic nanoparticles and methods of use thereof" was invented by Stefaan De Smedt (Mariakerke, Belgium), Rein Verbeke (Bruges, Belgium), Heleen Dewitte (Gentbrugge, Belgium) and Ine Lentacker (Ledeberg, Belgium).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a method and composition for optimized intracellular delivery of nucleic acids, in particular mRNA. In addition to mRNA, the composition, in particular a nanoparticle, may include a glycolipid antigen. Combinations with checkpoint inhibitors are also provided. The method and compositio...