ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,747,215, issued on Sept. 29, was assigned to Universite de Reims Champagne-Adrenne Reims (FR) (Reims, France), Inserm (Institut National de la Sante et de la Recherche Medicale (Paris), Universite de Rouen-Normandie (Mont-Saint-Aignan, France) and Centre National de la Recherche Scientifique (C.N.R.S.) (Paris).

"N2-arylmethyl-4-haloalkyl-pyridazin-3-one CFTR modulators for the treatment of cystic fibrosis" was invented by Stephane Gerard (Fismes, France), Jean-Philippe Bouillon (Fresquiennes, France), Abderrazzaq Bentaher (Saint Genis Laval, France), Eric Henon (Reims, France), Jacky Jacquot (Reims, France), Janos Sapi (Reims, France) and Frederic Velard (Heutregiville, France).

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