US Patent Issued to UNIVERSITAT ZURICH on July 28 for "CD25-biased anti-IL-2 antibody" (Swiss Inventors)

ALEXANDRIA, Va., July 28 -- United States Patent no. 12,692,306, issued on July 28, was assigned to UNIVERSITAT ZURICH (Zurich, Switzerland).

"CD25-biased anti-IL-2 antibody" was invented by Onur Boyman (Kusnacht, Switzerland), Ufuk Karakus (Zurich), Miro Raeber (Zurich), Roman Meledin (Dubendorf, Switzerland) and Robert Maka (Zurich).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides a human IL-2 (hIL-2)-specific monoclonal antibody, wherein a complex of hIL-2 and the monoclonal induces IL-2 signalling preferentially via CD25 and the trimeric IL-2R. The invention further provides a pharmaceutical composition comprising hIL-2 and said hIL-2-mAb for use treating inflammatory disease."

The p...