US Patent Issued to UNIVERSITAT REGENSBURG on March 31 for "Compositions for use in treating autosomal dominant BEST1-related retinopathies" (German Inventors)

ALEXANDRIA, Va., March 31 -- United States Patent no. 12,590,323, issued on March 31, was assigned to UNIVERSITAT REGENSBURG (Regensburg, Germany).

"Compositions for use in treating autosomal dominant BEST1-related retinopathies" was invented by Bernhard Weber (Obertraubling, Germany) and Andrea Milenkovic (Kofering, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention refers to a sgRNA molecule comprising a targeting domain for specifically targeting a SNP in the BEST1 coding region of a pathologic allele, wherein said targeting domain consists of a sequence selected from the group consisting of SEQ ID NO: 3-8, 41-44, 14-20, 50-52 and 54-55, or a sgRNA molecule combination of specifi...