ALEXANDRIA, Va., March 31 -- United States Patent no. 12,590,135, issued on March 31, was assigned to UNIVERSITAT FUR BODENKULTUR WIEN (Vienna).
"Stabilized extracellular domain of CD19" was invented by Elisabeth Laurent (Vienna), Michael Traxlmayr (Vienna) and Renate Kunert (Vienna).
According to the abstract* released by the U.S. Patent & Trademark Office: "An extracellular domain of CD19 (CD19-ECD) which comprises at least 90% sequence identity to SEQ ID NO:1, a first core region at positions 2-98 of SEQ ID NO:1, a second core region at positions 167-258 of SEQ ID NO:1, a third core region at positions 99-166 of SEQ ID NO:1, and at least one stabilizing point mutation at an amino acid position within said first and/or second and/or thi...