US Patent Issued to United Therapeutics on Nov. 3 for "Methods and compositions for improving endothelial cell barrier" (North Carolina, Michigan Inventors)

ALEXANDRIA, Va., Nov. 3 -- United States Patent no. 12,781,191, issued on Nov. 3, was assigned to United Therapeutics Corp. (Silver Spring, Md.).

"Methods and compositions for improving endothelial cell barrier" was invented by Bryan Fioret (Durham, N.C.), Thomas Petersen (Durham, N.C.), Ryan Bonvillain (Cary, N.C.), David Graham (Hillsborough, N.C.), Peter Vu (Raleigh, N.C.) and Lotte van den Goor (Ypsilanti, Mich.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are methods and compositions for use in improving a vascular barrier of endothelial cells. The methods may include the use of barrier agonist compounds and improved techniques for culturing endothelial cells. The improved methods and...