US Patent Issued to Ultragenyx Pharmaceutical on July 28 for "Methods and compositions for treating glycogen storage diseases" (Massachusetts, Ohio Inventors)

ALEXANDRIA, Va., July 28 -- United States Patent no. 12,692,512, issued on July 28, was assigned to Ultragenyx Pharmaceutical Inc. (Novato, Calif.).

"Methods and compositions for treating glycogen storage diseases" was invented by Christopher Tipper (Cambridge, Mass.), Kelly Reed Clark (Westerville, Ohio) and Samuel Wadsworth (Shrewsbury, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention provides a variety of novel adeno-associated virus (AAV) vectors for gene therapy applications in the treatment of glycogen storage disease type 1a (GSD-Ia). Disclosed herein are a number of recombinant nucleic acid molecules, vectors and recombinant AAV that incorporate a modified G6PC promoter/enhancer se...