ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,698,471, issued on Aug. 4, was assigned to UCL BUSINESS LTD (London).
"Live attenuated strain of Streptococcus pneumoniae and pharmaceutical compositions comprising a live attenuated strain of S. pneumoniae" was invented by Jeremy Brown (London) and Elisa Ramos-Sevillano (London).
According to the abstract* released by the U.S. Patent & Trademark Office: "A live attenuated strain of S. pneumoniae containing at least two genes or operons that have disrupted expression or encode for proteins that have impaired function, the two genes or operons being fhs, piaA, proABC, spxB, Sp_1288 and Sp_1027. Pharmaceutical compositions containing the live attenuated strains are also described. The l...