ALEXANDRIA, Va., Oct. 27 -- United States Patent no. 12,774,296, issued on Oct. 27, was assigned to TSINGHUA UNIVERSITY (Beijing) and BEIJING SYNTHETIC VACCINE BIOSCIENCES Co. LTD (Beijing).
"Substituted pyridin-2-amines as TLR8 agonists" was invented by Xuebin Liao (Beijing), Zhisong Wang (Beijing) and Yan Zhang (Beijing).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed in the present invention are a pyridine-2-amine derivative of Formula (I) and a pharmaceutical composition and use thereof. The pyridine-2-amine derivative can be used as a TLR8 selective agonist, has the characteristics of high selectivity, strong activity and high safety, can be used for preventing and/or treating diseases related t...