US Patent Issued to Trustees of Boston University on March 3 for "Compositions and methods for controlled mRNA translation and stability" (Massachusetts Inventors)

ALEXANDRIA, Va., March 3 -- United States Patent no. 12,565,665, issued on March 3, was assigned to Trustees of Boston University (Boston).

"Compositions and methods for controlled mRNA translation and stability" was invented by Alexander Michael Marzilli (Cambridge, Mass.) and John Tuan Ngo (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The technology described herein is directed to compositions, kits, systems and methods related to an engineered, inducible adenosine deaminase (iAD) enzymes, including but not limited to, an engineered inducible adenosine deaminase acting on RNA (ADAR) enzyme, which can be activated in the presence of an inducer. Also described are synthetic RNA molecules, ...