ALEXANDRIA, Va., Feb. 24 -- United States Patent no. 12,559,530, issued on Feb. 24, was assigned to Trustees of Boston University (Boston).

"Regulated synthetic gene expression systems" was invented by Ahmad S. Khalil (Lexington, Mass.), Wilson Wai Chun Wong (Brookline, Mass.), Divya Israni (Boston) and Huishan Li (Brookline, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The technology described herein is directed to regulated synthetic gene expression systems. In one aspect described herein are synthetic transcription factors (synTFs) comprising a DNA binding domain, a transcriptional effector domain, and a regulator protein. In other aspects described herein are gene expression systems comprising sa...