ALEXANDRIA, Va., Nov. 3 -- United States Patent no. 12,781,189, issued on Nov. 3, was assigned to Trestle Biotherapeutics Inc. (San Diego).
"Compositions and processes for engineering ureteric bud kidney tissues and in-vitro compositions thereof" was invented by Benjamin Shepherd (Encinitas, Calif.), Alice Chen (San Diego) and J. William Higgins III (Santee, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure provides compositions comprising engineered ureteric bud kidney tissues and methods of making lumenized ureteric bud kidney tissues. Also provided herein are in vitro kidneys comprising nephron progenitor cells and ureteric bud cells. Methods of making the compositions and in vitro kid...