ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,554, issued on March 17, was assigned to TRANSLATE BIO INC. (Waltham, Mass.).
"Methods for purification of messenger RNA" was invented by Frank DeRosa (Cambridge, Mass.), Anusha Dias (Cambridge, Mass.), Michael Heartlein (Cambridge, Mass.) and Shrirang Karve (Cambridge, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides, among other things, methods of purifying messenger RNA (mRNA) including the steps of subjecting an impure preparation comprising in vitro synthesized mRNA to a denaturing condition, and purifying the mRNA from the impure preparation from step (a) by tangential flow filtration, wherein the mRNA purif...