ALEXANDRIA, Va., July 7 -- United States Patent no. 12,673,086, issued on July 7, was assigned to TRANSLATE BIO INC. (Waltham, Mass.).
"Process and formulation of lipid nanoparticles" was invented by Frank DeRosa (Chelmsford, Mass.), Hardip R. Gopani (Acton, Mass.) and Shrirang Karve (Acton, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides an improved process for preparing a stable lyophilized composition comprising lipid nanoparticles encapsulating mRNA, which results in high mRNA integrity suitable for both short- and long-term storage for therapeutic use. In some embodiments, the present invention provides a method of preparing a stable lyophilized composition comprising...