ALEXANDRIA, Va., Feb. 17 -- United States Patent no. 12,553,043, issued on Feb. 17, was assigned to TRANSLATE BIO INC. (Waltham, Mass.).
"Methods and compositions for messenger RNA purification" was invented by Jonathan Abysalh (Lexington, Mass.), Jorel E. Vargas (Lexington, Mass.), Frank DeRosa (Lexington, Mass.) and Anusha Dias (Lexington, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides, among other things, methods for purifying mRNA, which involves removing impurities from a messenger RNA preparation synthesized by large scale invitro transcription process (IVT), by precipitating the IVT-synthesized mRNA in a buffer comprising a denaturing salt in combination with a red...