ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,698,258, issued on Aug. 4, was assigned to TRANSLATE BIO INC. (Waltham, Mass.).
"Cystine cationic lipids" was invented by Shrirang Karve (Lexington, Mass.), Saswata Karmakar (Lexington, Mass.) and Frank DeRosa (Lexington, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides, in part cystine cationic lipid compounds of formula A, and sub-formulas thereof: or a pharmaceutically acceptable salt thereof. The compounds provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly can be useful for treating various diseases, disorders and...