US Patent Issued to TigaTX on May 19 for "Engineered IgA antibodies and methods of use" (Dutch Inventors)

ALEXANDRIA, Va., May 19 -- United States Patent no. 12,630,650, issued on May 19, was assigned to TigaTX Inc. (Boston).

"Engineered IgA antibodies and methods of use" was invented by Jeanette Henrica Wilhelmina Leusen (Utrecht, Netherlands), Johannes Gerardus Maria Evers (Utrecht, Netherlands) and Geert Jan Van Tetering (Utrecht, Netherlands).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are engineered antibodies that comprise a modified IgA heavy chain constant region, pharmaceutical compositions, and methods of use. The engineered antibodies described herein comprise one or more amino acid substitution or deletion in a constant region of an IgA domain. Further provided herein are methods of...